CAY10580
Product Specifications
UNSPSC Description
CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM)[1].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cay10580.html
Purity
97.4
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCCCN1C(CCC(O)CCCCC)CCC1=O
Molecular Weight
341.49
References & Citations
[1]Billot X, et al. Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg Med Chem Lett. 2003;13(6):1129-1132. |[2]Olesen ET, et al. Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Proc Natl Acad Sci U S A. 2011;108(31):12949-12954. |[3]Ying F, et al. EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863(9):1029-1040.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-135259/CAY10580-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-135259/CAY10580-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
64054-40-6
Curated Selection
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