6-Aminophenanthridine
6-Aminophenanthridine inhibits the protein folding activity of the ribosome (PFAR) . 6-Aminophenanthridine competitively occludes the protein substrates from binding to rRNA and thereby inhibits PFAR[1].
Product Specifications
CAS Number
832-68-8
UNSPSC
12352005
Hazard Statement
H301-H319
Target
Prion Protein
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-aminophenanthridine.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C=CC=CC2=C(C=CC=C3)C3=N1
Molecular Formula
C13H10N2
Molecular Weight
194.23
Precautions
P264-P270-P280-P305+P351+P338-P330-P405-P501
References & Citations
[1]Pang Y, et al. The antiprion compound 6-aminophenanthridine inhibits the protein folding activity of the ribosome by direct competition. J Biol Chem. 2013;288 (26) :19081-19089.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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