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DC4

DC4, an ADC cytotoxin, can be used in the synthesis of antibody-drug conjugate (ADC) . DC4 can be used for the targeted treatment of cancer[1].

Product Specifications

CAS Number

615538-48-2

UNSPSC

12352203

Target

ADC Payload

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dc4.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N1)=CC2=C1C=CC(NC(CCS)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(OP(O)(O)=O)C7=CC=CC=C67)=O)=C4)C=C3

Molecular Formula

C34H29ClN5O7PS

Molecular Weight

718.12

References & Citations

[1]Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55 (2) :766-82.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Frequently Asked Questions

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