Methotrexate γ-Methyl Ester
Methotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519) [1].
Product Specifications
CAS Number
[67022-39-3]
Product Name Alternative
Methotrexate 5-methyl ester; γ-EMTX
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Antifolate
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/methotrexate-γ-methyl-ester.html
Purity
98.30
Solubility
10 mM in DMSO
Smiles
O=C(OC)CC[C@@H](C(O)=O)NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1)=O
Molecular Formula
C21H24N8O5
Molecular Weight
468.47
Precautions
H315, H319, H335
References & Citations
[1]James J Fort, et al. Transport and degradation characteristics of methotrexate diallsyl ester prodrugs across tape-stripped hairless mouse skin. Int J Pharm. 1993, 100 (1-3) : 233-239.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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