STK33-IN-1
STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC50 of 7 nM[1].
Product Specifications
CAS Number
1404437-49-5
UNSPSC
12352005
Target
STK33
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stk33-in-1.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1)=CC=C1N2N=CC3=CN=C(NC4=CC=C(N5CCN(C)CC5)C(OC)=C4)N=C32
Molecular Formula
C24H27N7O2
Molecular Weight
445.52
References & Citations
[1]Michel Weïwer, et al. A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells. ACS Med Chem Lett. 2012 Dec 13;3 (12) :1034-1038.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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