AA74-1
AA74-1 is a potent and selective inhibitor of APEH. AA74-1 significantly increases T cells proliferation by blocking the APEH activity[1].
Product Specifications
CAS Number
[1361532-00-4]
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aa74-1.html
Purity
99.9
Solubility
DMSO : 15 mg/mL (ultrasonic; warming)
Smiles
O=C(N1N=CC(C(CC(C)C)(O)CC(C)C)=N1)N2CCCC2
Molecular Formula
C16H28N4O2
Molecular Weight
308.42
References & Citations
[1]Adibekian A, et al. Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol. 2011 May 15;7 (7) :469-78.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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