Glycocholic acid-PEG10-iodoacetamide

Glycocholic acid-PEG10-iodoacetamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/glycocholic-acid-peg10-iodoacetamide.html

Solubility

10 mM in DMSO

Smiles

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)CCC(NCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CI)=O)=O)=O

Molecular Formula

C48H86IN3O15

Molecular Weight

1072.11

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562