Cobalt protoporphyrin IX

Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) [1].

Product Specifications

CAS Number

[14325-03-2]

Product Name Alternative

Co-PPIX

UNSPSC

12352005

Target

Influenza Virus; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cobalt-protoporphyrin-ix.html

Purity

70.0

Solubility

10 mM in DMSO

Smiles

CC1=C(CCC([O-])=O)C2=CC(C(CCC([O-])=O)=C3C)=[N]4C3=CC5=C(C)C(C=C)=C6C=C(C(C)=C7C=C)[N]8=C7C=C1[N-]2[Co+2]84[N-]56.[H+].[H+]

Molecular Formula

C34H32CoN4O4

Molecular Weight

619.58

References & Citations

[1]Ma LL, et al. heme oxygenase-1 agonist CoPP suppresses influenza virus replication through IRF3-mediated generation of IFN-α/β. Virology. 2019 Feb;528:80-88.