Ac-VDVAD-CHO
Product Specifications
UNSPSC Description
Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46 and 15 nM)[1].
Target Antigen
Casein Kinase
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage;Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-vdvad-cho.html
Solubility
10 mM in DMSO
Smiles
CC(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O)=O)=O
Molecular Weight
543.57
References & Citations
[1]Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134567/Ac-VDVAD-CHO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134567/
Clinical Information
No Development Reported
CAS Number
194022-51-0
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