Phylloflavan
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW 264.7 cells. Phylloflavan also inhibits the cytopathic effect of encephalomyocarditis virus on L929 fibroblast cells (38 U/mL) [1].
Product Specifications
CAS Number
[98570-83-3]
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/phylloflavan.html
Solubility
10 mM in DMSO
Smiles
O=C(C[C@@H](O)CCC1=CC(O)=C(O)C=C1)O[C@H]2CC3=C(O)C=C(O)C=C3O[C@@H]2C4=CC(O)=C(O)C=C4
Molecular Formula
C26H26O10
Molecular Weight
498.48
References & Citations
[1]Kolodziej H, et al. Proanthocyanidins and related compounds: antileishmanial activity and modulatory effects on nitric oxide and tumor necrosis factor-alpha-release in the murine macrophage-like cell line RAW 264.7. Biol Pharm Bull. 2001 Sep;24 (9) :1016-21.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-134467/Phylloflavan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-134467/
Scientific Category
Natural Products
Clinical Information
No Development Reported
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