Kinetin triphosphate
Kinetin triphosphate (6-Fu-ATP; KTP) is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate can be used in Parkinson's disease research[1].
Product Specifications
CAS Number
1450894-16-2
Product Name Alternative
6-Fu-ATP; KTP
UNSPSC
12352005
Target
PINK1/Parkin
Type
Reference compound
Related Pathways
Autophagy; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/kinetin-triphosphate.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(NCC4=CC=CO4)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O
Molecular Formula
C15H20N5O14P3
Molecular Weight
587.27
References & Citations
[1]Nicholas T Hertz, et al. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 2013 Aug 15;154 (4) :737-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Frequently Asked Questions
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