6-Me-ATP
6-Me-ATP (N6-Methyl-ATP) is a N6-modified ATP derivative. 6-Me-ATP shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide[1].
Product Specifications
CAS Number
3130-39-0
Product Name Alternative
N6-Methyl-ATP
UNSPSC
12352005
Target
GSK-3
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-me-atp.html
Solubility
10 mM in DMSO
Smiles
CNC1=C2N=CN([C@@H]3O[C@H](COP(O)(OP(OP(O)(O)=O)(O)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
Molecular Formula
C11H18N5O13P3
Molecular Weight
521.21
References & Citations
[1]Dong X, et al. Proteome-Wide Characterizations of N6-Methyl-Adenosine Triphosphate- and N6-Furfuryl-Adenosine Triphosphate-Binding Capabilities of Kinases. Anal Chem. 2021 Oct 5;93 (39) :13251-13259.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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