5'-O-DMTr-3'-O-methyl uridine-3'-CED-phosphoramidite
5'-O-DMTr-3'-O-methyl uridine-3'-CED-phosphoramidite is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Product Specifications
CAS Number
[179479-05-1]
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-o-dmtr-3-o-methyl-uridine-3-ced-phosphoramidite.html
Purity
98.01
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(C=C1)NC(N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)[C@@H](OC)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)=O
Molecular Formula
C40H49N4O9P
Molecular Weight
760.81
References & Citations
[1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20 (5) :218-25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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