8-Chloro-2'-deoxyadenosine
8-Chloro-2'-deoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].
Product Specifications
CAS Number
[85562-55-6]
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H315-H319-H335-H351-H361
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-chloro-2-deoxyadenosine.html
Solubility
10 mM in DMSO
Smiles
NC1=NC=NC2=C1N=C(Cl)N2[C@H]3C[C@H](O)[C@@H](CO)O3
Molecular Formula
C10H12ClN5O3
Molecular Weight
285.69
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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