AICAR-13C2,15N
Product Specifications
UNSPSC Description
AICAR-13C2,15N (Acadesine-13C2,15N; AICA Riboside-13C2,15N) is the 13C and 15N labeled AICAR (HY-13417)[1]. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[2][3].
Target Antigen
AMPK; Autophagy; Endogenous Metabolite; Isotope-Labeled Compounds; Mitophagy; YAP
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy;Epigenetics;Metabolic Enzyme/Protease;Others;PI3K/Akt/mTOR;Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/aicar-13c2-15n.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2[13C](N)=[13C]([15N]=C2)C(N)=O)O1
Molecular Weight
261.21
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13417S/AICAR-13C2-15N-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13417S/
Clinical Information
No Development Reported
CAS Number
1609374-70-0
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