2,5-Anhydro-D-glucitol-1,6-diphosphate

2,5-Anhydro-D-glucitol-1,6-diphosphate is a limited stimulator of yeast Pyruvate Kinase. 2,5-Anhydro-D-glucitol-1,6-diphosphate is used as an analogue of the a-form, 2,5-anhydro-D-mannitol 1,6-bisphosphate, while is an excellent allosteric activator of Pyruvate Kinase[1].

Product Specifications

CAS Number

[4429-47-4]

UNSPSC

12352005

Target

Pyruvate Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2-5-anhydro-d-glucitol-1-6-diphosphate.html

Purity

99.49

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@H](O)[C@H](COP(O)(O)=O)O[C@@H]1COP(O)(O)=O

Molecular Formula

C6H14O11P2

Molecular Weight

324.12

References & Citations

[1]Wurster B, et al. Tautomeric and anomeric specificity of allosteric activation of yeast pyruvate kinase by D-fructose 1, 6-bisphosphate and its relevance in D-glucose catabolism. FEBS Lett. 1976 Mar 15;63 (1) :17-21.