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2-O-Ethyl PAF C-16

2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR) ). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 to the PAF receptor with an IC50 of 21 nM[1].

Product Specifications

CAS Number

78858-42-1

UNSPSC

12352211

Hazard Statement

H315-H319-H335

Target

Platelet-activating Factor Receptor (PAFR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/2-o-ethyl-paf-c-16.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCOC[C@@H](OCC)COP(OCC[N+](C)(C)C)([O-])=O

Molecular Formula

C26H56NO6P

Molecular Weight

509.70

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Aoki Y, et al. A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor. J Immunol Methods. 1995 Oct 26;186 (2) :225-31.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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