2-O-Ethyl PAF C-16
2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR) ). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 to the PAF receptor with an IC50 of 21 nM[1].
Product Specifications
CAS Number
78858-42-1
UNSPSC
12352211
Hazard Statement
H315-H319-H335
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/2-o-ethyl-paf-c-16.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCCCOC[C@@H](OCC)COP(OCC[N+](C)(C)C)([O-])=O
Molecular Formula
C26H56NO6P
Molecular Weight
509.70
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Aoki Y, et al. A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor. J Immunol Methods. 1995 Oct 26;186 (2) :225-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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