Ara-ATP
Ara-ATP, a structural analog of ATP, inhibits poly (A) polymerase activity by competing with ATP[1].
Product Specifications
CAS Number
3714-60-1
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ara-atp.html
Solubility
10 mM in DMSO
Smiles
NC1=C2N=CN([C@@H]3O[C@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)[C@@H](O)[C@@H]3O)C2=NC=N1
Molecular Formula
C10H16N5O13P3
Molecular Weight
507.18
References & Citations
[1]Ghoshal K, Jacob ST. Ara-ATP impairs 3'-end processing of pre-mRNAs by inhibiting both cleavage and polyadenylation. Nucleic Acids Res. 1991 Nov 11;19 (21) :5871-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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