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Pilsicainide

Pilsicainide (SUN 1165 free acid) is a potent sodium channel blocker and potent class Ic antiarrhythmic agent[1][2].

Product Specifications

CAS Number

[88069-67-4]

Product Name Alternative

SUN 1165 (free base) ; Pilzicainide

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pilsicainide.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=C(C)C=CC=C1C)CC23CCCN2CCC3

Molecular Formula

C17H24N2O

Molecular Weight

272.39

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Yamakawa M, et al. Effect of sodium channel blocker, pilsicainide hydrochloride, on net inward current of atrial myocytes in thyroid hormone toxicosis rats. Thyroid. 2005 Jul;15 (7) :653-9.|[2]Plosker GL. Pilsicainide. Drugs. 2010 Mar 5;70 (4) :455-67.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Curated Selection

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