Mono (5-carboxy-2-ethylpentyl) phthalate-d4

Mono (5-carboxy-2-ethylpentyl) phthalate-d4 (MECPP-d4) is a deuterium labeled Mono (5-carboxy-2-ethylpentyl) phthalate (HY-133675) . Mono (5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di- (2-ethylhexyl) phthalate (DEHP) . Di (2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking[1][2][3].

Product Specifications

CAS Number

[866864-06-4]

Product Name Alternative

MECPP-d4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

OC(CCCC(CC)COC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(O)=O)=O)=O

Molecular Formula

C16H16D4O6

Molecular Weight

312.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Sjöberg P, et al. Effects of di- (2-ethylhexyl) phthalate and five of its metabolites on rat testis in vivo and in in vitro. Acta Pharmacol Toxicol (Copenh) . 1986;58 (3) :225-233.|[2]Van Vliet ED, et al. A review of alternatives to di (2-ethylhexyl) phthalate-containing medical devices in the neonatal intensive care unit [published correction appears in J Perinatol. 2012 Aug;32 (8) :648]. J Perinatol. 2011;31 (8) :551-560.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.