Bis-SS-C3-NHS ester

Bis-SS-C3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[98604-88-7]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bis-ss-c3-nhs-ester.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(ON1C(CCC1=O)=O)CCCSSCCCC(ON2C(CCC2=O)=O)=O

Molecular Formula

C16H20N2O8S2

Molecular Weight

432.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Disulfide Cleavable Linker

Available Sizes

Curated Selection

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