17-AEP-GA
17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin[1].
Product Specifications
CAS Number
75747-23-8
UNSPSC
12352203
Target
ADC Payload; HSP
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/17-aep-ga.html
Solubility
10 mM in DMSO
Smiles
O=C(C(NCCN1CCCC1)=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(C)/[C@H](OC(N)=O)[C@@H](OC)/C=C\C=C(C)\C3=O)C=C(N3)C2=O
Molecular Formula
C34H50N4O8
Molecular Weight
642.78
References & Citations
[1]Katarzyna Miekus, et al. 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. Oncol Rep. 2012 Nov;28 (5) :1903-9.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
HSP90; Traditional Cytotoxic Agents
Available Sizes
Frequently Asked Questions
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