PA-Nic (TFA)
PA-Nic TFA is a photoactivatable nicotine, whcih can be photolyzed with ~405 nm laser flashes to efficiently release nicotine[1].
Product Specifications
UNSPSC
12352005
Target
NAChR; Photosensitizer
Type
Reference compound
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pa-nic-tfa.html
Solubility
10 mM in DMSO
Smiles
C[N@+](CCC1)(CC2=CC(OC3=C2C=CC(N(CC(O)=O)CC(O)=O)=C3)=O)[C@@H]1C4=CC=CN=C4.OC(C(F)(F)F)=O.[O-]C(C(F)(F)F)=O
Molecular Formula
C28H27F6N3O10
Molecular Weight
679.52
References & Citations
[1]Matthew C Arvin, et al. Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine. J Vis Exp. 2019 Jan 25; (143) :10.3791/58873.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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