Bis-BCN-PEG1-diamide
Product Specifications
UNSPSC Description
Bis-BCN-PEG1-diamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-BCN-PEG1-diamide is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-bcn-peg1-diamide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCNC(COCC1C2C1CCC#CCC2)=O)COCC3C4CCC#CCCC43
Molecular Weight
484.63
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-133510/Bis-BCN-PEG1-diamide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-133510/
Clinical Information
No Development Reported
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