DBCO-C2-SulfoNHS ester
DBCO-C2-SulfoNHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-C2-SulfoNHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
1803279-86-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-c2-sulfonhs-ester.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(ON(C4=O)C(C(S(=O)(O)=O)C4)=O)=O
Molecular Formula
C23H18N2O8S
Molecular Weight
482.46
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Frequently Asked Questions
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