Mal-C2-cyclohexylcarboxyl-hydrazide (TFA)

Mal- C2-cyclohexylcarboxyl-hydrazide (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[359436-59-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-c2-cyclohexylcarboxyl-hydrazide-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C(C=CC1=O)N1CC2CCC(C(NN)=O)CC2.OC(C(F)(F)F)=O

Molecular Formula

C14H18F3N3O5

Molecular Weight

365.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP3-20842F 0.1 mL

Rabbit Monoclonal UCH-L1/PGP9.5 Antibody (UCHL1/7076R) [FITC]

Ask

View Details

168309 100 µg

Interferon-G (Interferon gamma, IFNG, IFN)

Ask

View Details

SR513874 1 Kit

Unc119 Rat siRNA Oligo Duplex (Locus ID 29402)

Ask

View Details

MBS8553811-01 0.1 mL

FDPS (Center) Rabbit pAb

Ask

View Details

MBS8553811-02 0.1 mL (AF405L)

FDPS (Center) Rabbit pAb

Ask

View Details

MBS8553811-03 0.1 mL (AF405S)

FDPS (Center) Rabbit pAb

Ask

View Details