4-Methyl-4- (pyridin-2-yldisulfanyl) pentanoic acid
4-Methyl-4- (pyridin-2-yldisulfanyl) pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1537891-69-2]
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-methyl-4-pyridin-2-yldisulfanyl-pentanoic-acid.html
Solubility
10 mM in DMSO
Smiles
OC(CCC(C)(C)SSC1=CC=CC=N1)=O
Molecular Formula
C11H15NO2S2
Molecular Weight
257.37
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Disulfide Cleavable Linker
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
