β-Estradiol-6-one 6- (O-carboxymethyloxime)
β-Estradiol-6-one 6- (O-carboxymethyloxime) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[35048-47-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/β-estradiol-6-one-6-o-carboxymethyloxime.html
Purity
99.67
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C/2=C1)[C@@]3([H])CC[C@@]([C@@H](O)CC4)(C)[C@]4([H])[C@]3([H])CC2=N/OCC(O)=O
Molecular Formula
C20H25NO5
Molecular Weight
359.42
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl-Chain Linkers
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