Endo-BCN-PEG3-NH2
Endo-BCN-PEG3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG3-NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
[1883512-27-3]
UNSPSC
12352211
Hazard Statement
H315, H319
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/endo-bcn-peg3-nh2.html
Purity
99.64
Solubility
10 mM in DMSO
Smiles
NCCOCCOCCOCCNC(OC[C@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O
Molecular Formula
C19H32N2O5
Molecular Weight
368.47
Precautions
H315, H319
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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