Endo-BCN-PEG3-NH2
Endo-BCN-PEG3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. endo-BCN-PEG3-NH2 is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
[1883512-27-3]
UNSPSC
12352211
Hazard Statement
H315, H319
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/endo-bcn-peg3-nh2.html
Purity
99.64
Solubility
10 mM in DMSO
Smiles
NCCOCCOCCOCCNC(OC[C@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O
Molecular Formula
C19H32N2O5
Molecular Weight
368.47
Precautions
H315, H319
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RPU43349-01 50 µg
Recombinant Human Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
Ask
View Details RPU43349-02 100 µg
Recombinant Human Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
Ask
View Details RPU43349-03 1 mg
Recombinant Human Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
Ask
View Details ![S100a5 Mouse Monoclonal Antibody [Clone ID: N176A/35]](https://cdn.genprice.uk/products/937/68dd1898061270361e8fb42c/imageurl/75-199.webp)