DSPE-PEG46-Folate

DSPE-PEG46-Folate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dspe-peg46-folate.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCC(OC[C@@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COP(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCC(NC(C1=CC=C(C=C1)NCC2=CN=C3N=C(N=C(O)C3=N2)N)=O)C(O)=O)=O)=O)(O)=O)=O

Molecular Formula

C153H284N9O60P

Molecular Weight

3240.89

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562