DSPE-PEG36-DBCO
Product Specifications
UNSPSC Description
DSPE-PEG36-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DSPE-PEG36-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dspe-peg36-dbco.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCCCCC(OC[C@@](OC(CCCCCCCCCCCCCCCCC)=O)([H])COP(OCCNC(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)=O)=O)(O)=O)=O
Molecular Weight
2664.29
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-133381/DSPE-PEG36-DBCO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-133381/
Clinical Information
No Development Reported
Curated Selection
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