DBCO-NHCO-PEG7-acid
DBCO-NHCO-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NHCO-PEG7-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-nhco-peg7-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCNC(CCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O
Molecular Formula
C36H48N2O11
Molecular Weight
684.77
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-13968R-PE-Cy7 100 µL
CHST7 Polyclonal Antibody, PE-Cy7 Conjugated
Sign In for Pricing
View Details 
123214-HRP 100 µL
ALDH5A1 (Succinate-semialdehyde Dehydrogenase, Mitochondrial, Aldehyde Dehydrogenase Family 5 Member A1, NAD (+) -dependent Succinic Semialdehyde Dehydrogenase, SSADH) (HRP)
Sign In for Pricing
View Details 
LV681571 1.0 µg DNA
MGC125239 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 