DBCO-NHCO-PEG6-amine
DBCO-NHCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DBCO-NHCO-PEG6-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dbco-nhco-peg6-amine.html
Solubility
10 mM in DMSO
Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCNC(CCOCCOCCOCCOCCOCCOCCN)=O
Molecular Formula
C33H45N3O8
Molecular Weight
611.73
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15089288 1 Vial
Lentiviral human SH3BP2 shRNA (UAS) - Lentiviral human SH3BP2 shRNA (UAS, GFP) (25)
Sign In for Pricing
View Details 
D8065-31F-PE 200 µL
DPP8, CT (Dipeptidyl Peptidase 8, DP8, Dipeptidyl Peptidase VIII, DPP VIII, Prolyl Dipeptidase DPP8, Dipeptidyl Peptidase IV-related Protein 1, DPRP-1, MSTP141, DPRP1, MSTP097, MSTP135) (PE) discontinued
Sign In for Pricing
View Details