Propargyl-PEG10-amine
Propargyl-PEG10-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG10-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2112737-25-2]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg10-amine.html
Purity
99.66
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
Molecular Formula
C23H45NO10
Molecular Weight
495.60
Precautions
H302, H315, H319, H335
References & Citations
[1]Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
(E) - (8S,9S,10S,13S,14S,17R) -17-Ethynyl-10-hydroperoxy-13-methyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl hex-3-enoate
