HDDAH-1-IN-1 (TFA)
HDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 μM[1].
Product Specifications
CAS Number
1229238-70-3
UNSPSC
12352211
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hddah-1-in-1-tfa.html
Solubility
10 mM in DMSO
Smiles
N=C(NCCOC)NCCCCN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
Molecular Formula
C12H22F6N4O5
Molecular Weight
416.32
References & Citations
[1]Lunk I, et al. Discovery of N- (4-Aminobutyl) -N'- (2-methoxyethyl) guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1) . J Med Chem. 2019 Dec 31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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