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HDDAH-1-IN-1 (TFA)

HDDAH-1-IN-1 TFA (compound 8a) is a potent and selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1), with a Ki of 18 μM[1].

Product Specifications

CAS Number

1229238-70-3

UNSPSC

12352211

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hddah-1-in-1-tfa.html

Solubility

10 mM in DMSO

Smiles

N=C(NCCOC)NCCCCN.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

Molecular Formula

C12H22F6N4O5

Molecular Weight

416.32

References & Citations

[1]Lunk I, et al. Discovery of N- (4-Aminobutyl) -N'- (2-methoxyethyl) guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase-1 (hDDAH-1) . J Med Chem. 2019 Dec 31.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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