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(Rac) -BAY-985

(Rac) -BAY-985 (Compound Example 100.01) is a potent, ATP-competitive and selective TBK1 inhibitor with an IC50 of 1.5 nM. Antitumor efficacy[1].

Product Specifications

CAS Number

2101925-20-4

UNSPSC

12352005

Target

IKK

Type

Reference compound

Related Pathways

NF-κB

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rac-bay-985.html

Solubility

10 mM in DMSO

Smiles

O=C(N1CCN(C(C2=CC(NC3=NC4=CC=C(C5=NC=NC(N(C)C)=C5)C=C4N3)=NC=C2)C)CC1)CC(F)(F)F

Molecular Formula

C27H30F3N9O

Molecular Weight

553.58

References & Citations

[1]Volker Schulze, et al. Heteroarylbenzimidazole compounds. WO2017102091A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

TBK1

Frequently Asked Questions

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