14-Norpseurotin

14-Norpseurotin is a compound isolated from the culture of Aspergillus fumigatus. 14-Norpseurotin significantly induces neurite outgrowth of rat pheochromocytoma cells (PC12) at a 10.0 microM concentration[1].

Product Specifications

CAS Number

[1031727-34-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/14-norpseurotin.html

Solubility

10 mM in DMSO

Smiles

O=C(N1)[C@@](OC([C@@H](O)[C@@H](O)/C=C\C)=C2C)(C2=O)[C@@H](O)[C@]1(OC)C(C3=CC=CC=C3)=O

Molecular Formula

C21H23NO8

Molecular Weight

417.41

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1] Ge HM, et al. Bioactive alkaloids from endophytic Aspergillus fumigatus. J Nat Prod. 2009;72 (4) :753-755.|[2]Bonday ZQ, et al. LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Med Chem Lett. 2018;9 (7) :612-617.