(E) -5-Hydroxyferulic acid
(E) -5-Hydroxyferulic acid is the E-isomer of 5-Hydroxyferulic acid. 5-hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrat[1][2][3].
Product Specifications
CAS Number
110642-42-7
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
COMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/e-5-hydroxyferulic-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(O)/C=C/C1=CC(OC)=C(O)C(O)=C1
Molecular Formula
C10H10O5
Molecular Weight
210.19
Precautions
H315, H319, H335
References & Citations
[1]Parvathi K, et al. Substrate preferences of O-methyltransferases in alfalfa suggest new pathways for 3-O-methylation of monolignols. Plant J. 2001 Jan;25 (2) :193-202.|[2]Maury S, et al. Tobacco O-methyltransferases involved in phenylpropanoid metabolism. The different caffeoyl-coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase classes have distinct substrate specificities and expression patterns. Plant Physiol. 1999 Sep;121 (1) :215-24.|[3]Inoue K, et al. Substrate preferences of caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferases in developing stems of alfalfa (Medicago sativa L.) . Arch Biochem Biophys. 2000 Mar 1;375 (1) :175-82.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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