DNMT-IN-1

DNMT-IN-1 is a potent DNMT inhibitor with an EC50 value of 3.2 µM. DNMT-IN-1 shows antiproliferative active[1].

Product Specifications

CAS Number

[2396691-28-2]

UNSPSC

12352005

Target

DNA Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dnmt-in-1.html

Solubility

10 mM in DMSO

Smiles

Br[C@@]1([N+]([O-])=O)[C@@H](C2=C([N+]([O-])=O)C=CC=C2)OC3=CC=CC=C3C1=O

Molecular Formula

C15H9BrN2O6

Molecular Weight

393.15

References & Citations

[1]Pechalrieu D, et al. Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells. Eur J Med Chem. 2020 Jan 15;186:111829.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DNA Methyltransferase

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