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PI3K-IN-9

PI3K-IN-9 (compound 1-14) is a potent and selective PI3Kδ inhibitor with an IC50 of 8.9 nM[1].

Product Specifications

CAS Number

[2360875-63-2]

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi3k-in-9.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1C[C@H]1C)N(CC2)[C@H](C)CN2C3=CN=C(C#N)C(C4=CN(C)N=C4)=N3

Molecular Formula

C19H23N7O

Molecular Weight

365.43

References & Citations

[1]Meredeth A. MCGOWAN, et al. Inhibiteurs puriques de la phosphatidylinositol 3-kinase delta humaine. WO2019125839.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI3Kδ

Curated Selection

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