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MPC-3100

Product Specifications

UNSPSC Description

MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with potential antineoplastic activity[1].

Target Antigen

HSP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mpc-3100.html

Purity

98.3

Solubility

DMSO : 5.5 mg/mL (ultrasonic;warming)

Smiles

NC1=C2C(N(CCC3CCN(C([C@@H](O)C)=O)CC3)C(SC4=C(Br)C=C(OCO5)C5=C4)=N2)=NC=N1

Molecular Weight

549.44

References & Citations

[1]Kim SH, et al. Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor. J Med Chem. 2012 Sep 13;55(17):7480-501.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-13301/MPC-3100-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-13301/MPC-3100-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

958025-66-6

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