MPC-3100
MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with potential antineoplastic activity[1].
Product Specifications
CAS Number
[958025-66-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mpc-3100.html
Purity
98.36
Solubility
DMSO : 5.5 mg/mL (ultrasonic; warming)
Smiles
NC1=C2C(N(CCC3CCN(C([C@@H](O)C)=O)CC3)C(SC4=C(Br)C=C(OCO5)C5=C4)=N2)=NC=N1
Molecular Formula
C22H25BrN6O4S
Molecular Weight
549.44
Precautions
H315, H319, H335
References & Citations
[1]Kim SH, et al. Discovery of (2S) -1-[4- (2-{6-amino-8-[ (6-bromo-1,3-benzodioxol-5-yl) sulfanyl]-9H-purin-9-yl}ethyl) piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor. J Med Chem. 2012 Sep 13;55 (17) :7480-501.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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