KRAS G12C inhibitor 18
Product Specifications
UNSPSC Description
KRAS G12C inhibitor 18 is a potent and orally active KRAS G12C inhibitor. Anti-tumor activities[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-18.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(N)SC2=CC=CC(C3=C(F)C=C(C(N4[C@@](CN(CC4)C(C=C)=O)([H])CCO5)=O)C5=C3Cl)=C12
Molecular Weight
510.97
References & Citations
[1]Serge Louis Boulet, et al. Kras g12c inhibitors. WO2021118877A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132979/KRAS-G12C-inhibitor-18-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132979/
Clinical Information
No Development Reported
CAS Number
2649788-45-2
Curated Selection
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