KRAS G12C inhibitor 18
KRAS G12C inhibitor 18 is a potent and orally active KRAS G12C inhibitor. Anti-tumor activities[1].
Product Specifications
CAS Number
[2649788-45-2]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kras-g12c-inhibitor-18.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(N)SC2=CC=CC(C3=C(F)C=C(C(N4[C@@](CN(CC4)C(C=C)=O)([H])CCO5)=O)C5=C3Cl)=C12
Molecular Formula
C25H20ClFN4O3S
Molecular Weight
510.97
References & Citations
[1]Serge Louis Boulet, et al. Kras g12c inhibitors. WO2021118877A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
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