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KRAS G12C inhibitor 18

Product Specifications

UNSPSC Description

KRAS G12C inhibitor 18 is a potent and orally active KRAS G12C inhibitor. Anti-tumor activities[1].

Target Antigen

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein;MAPK/ERK Pathway

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kras-g12c-inhibitor-18.html

Solubility

10 mM in DMSO

Smiles

N#CC1=C(N)SC2=CC=CC(C3=C(F)C=C(C(N4[C@@](CN(CC4)C(C=C)=O)([H])CCO5)=O)C5=C3Cl)=C12

Molecular Weight

510.97

References & Citations

[1]Serge Louis Boulet, et al. Kras g12c inhibitors. WO2021118877A1.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-132979/KRAS-G12C-inhibitor-18-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-132979/

Clinical Information

No Development Reported

CAS Number

2649788-45-2

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