TrxR-IN-2

TrxR-IN-2, a potential thioredoxin reductase (TrxR) inhibitor, represents a promising candidate drug for the chemoresearch of drug-resistant hepatocellular carcinoma.

Product Specifications

CAS Number

[2866261-50-7]

UNSPSC

12352005

Target

TrxR

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/trxr-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C1C=CCCN1C(/C=C/C2=NC(C)=C(/C=C/C(N3CCC=CC3=O)=O)N=C2C)=O

Molecular Formula

C22H22N4O4

Molecular Weight

406.43

References & Citations

[1]Qian J, et al. A Derivative of Piperlongumine and Ligustrazine as a Potential Thioredoxin Reductase Inhibitor in Drug-Resistant Hepatocellular Carcinoma. J Nat Prod. 2021 Nov 21.