BRD4 ligand-Linker Conjugate 1
BRD4 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs. BRD4 ligand-Linker Conjugate 1 consists of BRD4 Degrader CFT-2718 and
Product Specifications
CAS Number
[2154358-89-9]
UNSPSC
12352005
Target
Target Protein Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-ligand-linker-conjugate-1.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C2=NC3(CC3)C4=NN=C(C)N4C5=CC=C(C6=CN(CCCCCCN)N=C6)C=C25)C=C1
Molecular Formula
C28H30ClN7
Molecular Weight
500.04
References & Citations
[1]Sun D, et al. Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models. Mol Cancer Ther. 2021 Aug;20 (8) :1367-1377.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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