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BRD4 ligand-Linker Conjugate 1

BRD4 ligand-Linker Conjugate 1 is a target protein ligand-linker conjugate that can be used in the synthesis of PROTACs. BRD4 ligand-Linker Conjugate 1 consists of BRD4 Degrader CFT-2718 and

Product Specifications

CAS Number

[2154358-89-9]

UNSPSC

12352005

Target

Target Protein Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brd4-ligand-linker-conjugate-1.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C2=NC3(CC3)C4=NN=C(C)N4C5=CC=C(C6=CN(CCCCCCN)N=C6)C=C25)C=C1

Molecular Formula

C28H30ClN7

Molecular Weight

500.04

References & Citations

[1]Sun D, et al. Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models. Mol Cancer Ther. 2021 Aug;20 (8) :1367-1377.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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