2-(2,6-Dioxopiperidin-3-yl)phthalimidine-C5-Br
Product Specifications
UNSPSC Description
2-(2,6-Dioxopiperidin-3-yl)phthalimidine-C5-Br is a E3 ligase ligand-linker conjugate for PROTAC.
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-2-6-dioxopiperidin-3-yl-phthalimidine-c5-br.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N(CC1=C2C=CC=C1CCCCCBr)C2=O)CC3)NC3=O
Molecular Weight
393.27
References & Citations
[1]Wei D, et al. Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14822-14847.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132939/2-2-6-Dioxopiperidin-3-yl-phthalimidine-C5-Br-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132939/
Clinical Information
No Development Reported
CAS Number
2411022-24-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
