2- (2,6-Dioxopiperidin-3-yl) phthalimidine-C5-Br

2- (2,6-Dioxopiperidin-3-yl) phthalimidine-C5-Br is a E3 ligase ligand-linker conjugate for PROTAC.

Product Specifications

CAS Number

[2411022-24-5]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-2-6-dioxopiperidin-3-yl-phthalimidine-c5-br.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N(CC1=C2C=CC=C1CCCCCBr)C2=O)CC3)NC3=O

Molecular Formula

C18H21BrN2O3

Molecular Weight

393.27

References & Citations

[1]Wei D, et al. Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer. J Med Chem. 2021 Oct 14;64 (19) :14822-14847.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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