(S, R, S) -AHPC-Me-decanedioic acid
(S, R, S) -AHPC-Me-decanedioic acid is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.
Product Specifications
CAS Number
2380273-45-8
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-me-decanedioic-acid.html
Solubility
10 mM in DMSO
Smiles
OC(CCCCCCCCC(N[C@H](C(N1C[C@@H](C[C@H]1C(N[C@@H](C)C2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C)=O)=O
Molecular Formula
C33H48N4O6S
Molecular Weight
628.82
References & Citations
[1]Pal P, et al. Discovery of a Novel BCL-XL PROTAC Degrader with Enhanced BCL-2 Inhibition. J Med Chem. 2021 Oct 14;64 (19) :14230-14246.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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